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Experimental data extracted by the Richard Scheltema lab includes spatial information (crosslinks) and PTMs (phosphorylation, acetylation, etc). By collaborating with other structural techniques like Cryo-EM precise protein models are constructed.

The ScheltemaLAB, headed by Richard Scheltema, focusses on Structural Proteomics, with the aim of identifying therapeutic targets by resolving protein & protein complex structures. The developed techniques have not only been disseminated in many scientific publications, but also commercialized. This includes mass spectrometry data analysis software, protein structure interpretation, and novel reagents.

Curious about the work? Check our google scholar or the software & chemistry sections.